The human body has the same neurones in the brain and receptors in the brain and gut, say the researchers - suggesting that the mechanism may result in 'compensation' after consuming food and drink containing zero-calorie sweeteners.

Brain hormone could help distinguish sugar and zero calorie sweeteners

By Nathan Gray

Fruit flies have a set of neurones that fire only when they encounter real sugar – triggering the release of a hormone that is not released when they eat a non-calorific sweetener. And researchers suggest that humans possess the same ‘molecular machinery’.